Acellular versus Whole-Cell Pertussis Vaccines
نویسندگان
چکیده
منابع مشابه
Whole-cell and acellular pertussis vaccines.
OBJECTIVE To provide a review of pertussis vaccines, including information on efficacy, adverse reactions, and antibody production following administration of both whole-cell and acellular pertussis vaccines. DATA SOURCES A MEDLINE search and extensive review of journals was conducted to identify the information for this review. DATA EXTRACTION Pertinent studies reporting experience with pe...
متن کاملComparative Effectiveness of Acellular Versus Whole-Cell Pertussis Vaccines in Teenagers
BACKGROUND: During the 1990s, the United States switched from combined diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines to combined acellular pertussis (DTaP) vaccines because of safety concerns. After a 2010–2011 pertussis outbreak, we sought to evaluate whether disease risk in 10 to 17 year olds differed between those who previously received DTwP from those who received DTaP....
متن کاملComparative effectiveness of acellular versus whole-cell pertussis vaccines in teenagers.
BACKGROUND During the 1990s, the United States switched from combined diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines to combined acellular pertussis (DTaP) vaccines because of safety concerns. After a 2010-2011 pertussis outbreak, we sought to evaluate whether disease risk in 10 to 17 year olds differed between those who previously received DTwP from those who received DTaP. ...
متن کاملComparative Effectiveness of Acellular Versus Whole-Cell Pertussis Vaccines in Teenagers
BACKGROUND: During the 1990s, the United States switched from combined diphtheria, tetanus toxoids, whole-cell pertussis (DTwP) vaccines to combined acellular pertussis (DTaP) vaccines because of safety concerns. After a 2010–2011 pertussis outbreak, we sought to evaluate whether disease risk in 10 to 17 year olds differed between those who previously received DTwP from those who received DTaP....
متن کاملAcellular pertussis vaccines pertinent issues.
Efficacy of whole cell pertussis vaccines (wP) in humans correlates with (and hence is measured by) the ‘mouse protection test’, wherein vaccinated mice are challenged with live B. pertussis. This test does not work similarly with acellular pertussis vaccines (aP); hence antibody levels to various antigens are measured as a surrogate marker of efficacy. This difference between the direct as com...
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ژورنال
عنوان ژورنال: Canadian Journal of Infectious Diseases
سال: 1992
ISSN: 1180-2332
DOI: 10.1155/1992/564683